Revision as of 18:44, 4 February 2013

MRI RFP

http://www.nsf.gov/pubs/2013/nsf13517/nsf13517.htm

Highlights.

"MRI is not used to buy a suite of insturments to outfit research laboratories/facilities or be used to conduct independent research activities simultaneously".

"MRI is used for a single insturment or when combined serves as an integrated instrument."

The photon flux monitor when combined with the rabbit will be an instrument for both isotope production and PAA analysis research. The tool will have inter-disciplinary uses ranging from engineering to archeology.

Track1: Acquisition of a single instrument

Track2: development of a single instrument or for equipment that when combined serves as an integrated instrument.

We will be track 2. The combined equipment will be an integrated instrument for the production of Isotopes to be used in research and industry. The devise will also be an instrument for PAA analysis.

Proposal

NSF-MRI_2013

The proposal will ask for a robot to move the sample from the trolley system into a pig because the holder may be activated as well as the sample.

A row of CVD detectors will be used to scan the photon field at low electron currents which will reduce the maximum photon flux to 10^9.

An array of CVD detector will be place downstream of the sample to monitor the flux as the electron current is increased to maximize the photon flux on the target. The position of the target can also be monitored with respect to the photon flux field as the field decreases to to the target absorbing photons.

Purpose

In June of 2012, the Idaho Accelerator Center received a grant from the state of Idaho as part of the Idaho Global Entrepreneurial Mission (IGEM) program. One of the proposed objectives was to research the use of an electron accelerator to produce Copper isotopes for medical diagnostic procedures. Preliminary results of the work sponsored by this research have indicated that the production of Copper isotopes strongly depends on the alignment of the incident radiation to the sample. While a two cm sample size may produce the highest number of isotopes per volume, a missalignment of more than a centimeter may reduce the amount of isotopes produced by a factor of at least two. A strong need now exists for a system to monitor the spatial distribution of the photons used to irradiate the samples. Based on these results, we propose the development of an irradiation instrument, that qualifies for the MRI category "Track 2", to be used for isotope production and PAA analysis.

The proposed instrument will be composed of a photon beam monitoring system and a sample conveyor. Support from this MRI will be used to construct the photon monitoring system. Matching support from the IGEM project will be used for the sample conveyor system. The conveyor, commonly referred to as a rabbit, will transport samples into the irradiation region and then to a shielded container (lead pig) after irradiation. The transportation system is a necessity due to the high activity isotopes that may be produced. When used as an instrument for PAA, the transportation system will eliminate the step of shutting the accelerator off in order to change to the control sample thereby risking a change in the experimental conditions whose uniformity is essential for meaningful measurements. Once calibrated, the photon monitoring system would allow users to irradiate sample with a known amount of radiation.

The proposed instruments ability to enhance the production of copper isotopes for medical diagnostic tests is only one potential use. Isotope production in the US is a $$$ busines..

Paragraph of the instruments impact on the production of isotopes.

Using the instrument for PAA and the large potential user base.

The University of Missouri's Research Reactor is a current producer of medical isotopes with a total operating budget o

Talking points

1.) The accelerator "Jack" is an instrument for PAA and isotope production

2.) Isotope production impact on other areas of research (medical, fracking, underground pipelines, spikants for homeland security)

3.) Inter organizational use of PAA ( Geology, Archeology, certification for coffee origins....)

4.) Impact of Photon Flux monitoring for PAA analysis

5.) Device will train accelerator physicists, nuclear chemists, ...

What is the difference between time-like and spacelike Feynman diagram

Minnesota Lunar Simulant

PAA was used to determine the trace elements present in the Minnessota Lunar Simulant 1 (MLS-1) material synthesized to approximate soil sample 10084 from the Apollo 11 mare material. Synthesized materials, like MLS-1, were produced to aide in the development of next generation lunar technologies for future lunar missions. Workshops were held to identify and define lunar regolith simulant materials for this purpose. Figure XXX quantifies PAA's ability to measure the trace elements of this material and contrasts those measurements with

In 2005, the Marshal Space Flight Center and the Johnson Space Center held a workshop to identify and define lunar regolith simulant materials that would be needed for the development of next generation lunar technologies to support future missions. This workshop was a follow up to a 1989 workshop that led to the development the lunar simulants MLS-1 and JSC-1. The PAA survey of this material was compared with Three moon dust simulant samples were irradiate for a PPA analysis and compared to a reference study.

[\ref L. Sibille, "Lunar Regolith Simulant Materials, Recommendations for Standardization, Production, and Usage", NASA TP, 2005]

http://isru.msfc.nasa.gov/lib/Documents/PDF%20Files/LRSM_docs/LRSM_Abstract_Book.pdf

Table 4.3B (pg 4-13) in the reference below has the trace element data for MLS-1 as attribute to Tucker and Setzer (1991) http://isru.msfc.nasa.gov/lib/Documents/PDF%20Files/Final_LSRM_Report_12-9-05.pdf

D. Tucker and A. Setzer, "Differential Thermal Analysis of Lunar Soil Simulant", NASA Technical Memorandum TM-103563, 1991

http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19920006733_1992006733.pdf

File:MLS-1 PAAresults.xmgrac.txt

Budget

Equipment list

two steps

1.) purchase 16, single crystal detectors from http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf. These will serve as monitors distributed symmetrically around the beam line and used to steer the electron beam until equal photon rates are observed => centered photon beam.

2.) A wire tungsten wire coated with diamond will sweep through the photon beam in the location of the target to measure the photon flux.

get http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf to build a pixelated 3 x 3 cm detector with .5 x .5 cm size pixels (36 pixels)

OR if the photon flux is too high construct a wire array.

Cost	Device	Purpose
50,000	BPMs	4 electron beam position monitors
20,000	16, CVD Diamond detector	Off the shelf single crystal single pixel detector pg 49 in[ http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf]
10,000	20 , 5 x 5 mm^2 CVD films	films for pixel detector array or wire (tungsten coated with diamond) scanner
10,000	Circuitry	PCB board, connectors, and single crystal mounting by external vendor
30,000	beam time	3 weeks of beam time to test device and measure performance
$28,000	DAQ	VME based DAQ system with EPICs monitoring, 32 channel ADC ($6k), ROC($3k), MiniCrate($4k), Server ($2k), Tigger supervisor ($3k), NIM Discriminator /Trigger/ECL output module ($10k)
$10k Cost Share	Beam Line components	Steering coils ($1k), power supplies ($4k), and Beam line components($5k) to install BPMs
$160k Cost Share	Rabbit	sample conveyor system from IGEM grant

Proposed Budget: $148k + $160k (Cost share) = $308k

Equipment

Detectors

Erich Griesmayer

http://www.cividec.at http://www.cividec.at/#products.html

Prof. Dr. Erich Griesmayer CIVIDEC Instrumentation GmbH Schottengasse 3A/1/41 A - 1010 Wien Mobile: +43 664 1066840 Fax: +43 1 9223619 www.cividec.at

Element 6 office in Snata Clara, Ca Thomas Obeloer. Thomas.Obeloer@e6.com

Simon Mathias; Element 6 UK office Product Manager - Mechanical and New Applications Element Six Technologies Phone: + 44-1344 638209 Mobile: + 44-7557 995644 http://www.e6.com/ Technologies Element Six Ltd., Kings Ride Park, Ascot, Berkshire, SL5 8BP, UK

BPMs

Bergoz Instrumentation:

S-BPM = $4080 Euros S-BPM-FEFA = $1260 Euros

the other accessories are also desired

File:Bergoz BPM PriceList 2012.pdf

Permanent magnet

Off the shelf

A M-25 5 kGauss permanent magnet with a footprint of 4" x 3" could be placed between the radiator and the isotope target on Jack.

http://www.mmr-tech.com/comp_electromagnets.php

The gap is 0.75" so it to would need to go in the vacuum. We would need to determine how much the beam spot blows up after leaving the converter and how high the photon flux is in the sample region after the 3" distance is taken up by the magnet.

Custom

The vendor below has stated that they have the ability to design a permanent magnet to our specification.

http://www.duramag.com/request-a-quote.html

The above vendor needs a CAD drawing showing the dimensions of a magnet that would work for isotope production on Jack in order to provide a quote.

Transport system samples

http://www.asi.com/auto-industrial/overhead-conveyors/monorail.php

References

Nitrogen tracers: N-15 is rare. If you dope nitrogen sources with it you can see where the leak into environment. This is a stable tracer so it would be able to monitor long time plume expansions.

Catchment hydrology

Review of Diamond detectors

http://www.ifh.de/~akg/phys/tapper.pdf

Simulations

http://www.osti.gov/energycitations/product.biblio.jsp?query_id=1&page=0&osti_id=20658046

High Flux MeV photon profiler

http://accelconf.web.cern.ch/accelconf/p99/PAPERS/WEA90.PDF

http://ieeexplore.ieee.org/ielx5/5379507/5398121/05398374.pdf?tp=&arnumber=5398374&isnumber=5398121

CVD Diamond film

Film Vendor only

http://www.e6cvd.com/cvd/page.jsp?pageid=415

Alemeda Applied Sciences Corporation

http://www.aasc.net/drds http://www.aasc.net/media/DRD-AppNote.pdf

Diamond x-ray view screen http://www.diamond-materials.com/EN/products/cvd_for_xray/fluorescence_beam_monitors.htm

http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf

NIM paper from 2002

http://144.206.159.178/ft/787/47160/14168748.pdf

Diamond Detectors LtD (Vendor for single crystal Chip on Board Package)

http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf

Medical isotopes

Market report forcasting -> 2015

http://www.prnewswire.com/news-releases/global-nuclear-medicine-medical-isotopesradioisotopesradiopharmaceuticals-market-in-petspect-imaging--therapy---competitive-landscape-current-trends--forecasts-2010-2015-139005529.html

2013 DOE Medical Isotope program budget and info

http://science.energy.gov/~/media/budget/pdf/sc-budget-request-to-congress/fy-2013/Cong_Budget_2013_IsoptopeProductionandDistributionProgramFunding.pdf

2010 Talk on Future Isotope needs in medicine and industry

http://www.nscl.msu.edu/~mantica/radio-frib/runde-acsboston.pdf

Need Mo-99, Tc-99m, I-131, I-125, Cu-67, At-211, Ac-225, Bi-213, Am-241, Gd-148, Sr-90, Pm-147

A big isotope supplier is Eckert & Ziegler

http://www.ezag.com/fileadmin/ezag/user-uploads/pdf/analyses-englisch/concord_e_01.pdf

2009 Medical Isotope industry & trade study

http://www.usitc.gov/publications/332/ITS-1.pdf

Fracking

http://www.shalegas.energy.gov/resources/111811_final_report.pdf

Earth Justice

http://earthjustice.org/features/campaigns/fracking-across-the-united-states

http://www.drillingmaps.com/fracking.html#.UQq-QKUlZ6I

Artificially-produced Isotope List

Jeff H. Shelton Isotope Business Office (IBO) National Isotope Development Center (NIDC) Telephone: (865) 576-6401 E-mail: EF6 or sheltonjh@ornl.gov

Cobalt-60, Lanthanum-140, Scandium-46, Silver-110m, Gold-198: Used together in blast furnaces to determine resident times and to quantify yields to measure the furnace performance.

Industrial

Isotope	Production Reaction	Use
Am-241		Used in backscatter gauges, smoke detectors, fill height detectors and in measuring ash content of coal.
Cesium-137		Used for radiotracer technique for identification of sources of soil erosion and deposition, in density and fill height level switches.
Chromium 57		Used to label sand to study coastal erosion.
Cobalt-60		Used for gamma sterilisation, industrial radiography, density and fill height switches.
Gadolinium-148
Gold-198		Used to study sewage and liquid waste movements, as well as tracing factory waste causing ocean pollution, and to trace sand movement in river beds and ocean floors.
Iridium-192		Fracking ,Used in gamma radiography to locate flaws in metal components.
Krypton-85		Used for industrial gauging.
Manganese-54		Used to predict the behaviour of heavy metal components in effluents from mining waste water.
Nickel-63		Used in light sensors in cameras and plasma display, also electronic discharge prevention and in electron capture detectors for thickness gauges.
Pm-147
Selenium-75		Used in gamma radiography and non-destructive testing.
Strontium-90		Used for industrial gauging
Technetium-99m		Used to study sewage and liquid waste movements, as well as tracing factory waste causing ocean pollution, and to trace sand movement in river beds and ocean floors.
Thallium-204		Used for industrial gauging.
Ytterbium-169		Used in gamma radiography and non-destructive testing.
Zinc-65		Used to predict the behaviour of heavy metal components in effluents from mining waste water.

Medical

Cesium-137 || || Used for radiotracer technique for identification of sources of soil erosion and deposition, in density and fill height level switches.

Isotope	Production Reaction	Use
Mo-99		Medical
Tc-99m		Medical
Tl-201		Medical Thalilum is most common substitute for Tc
I-131
I-125
Cu-67
Ac-225
Bi-213
Am-241		Used in backscatter gauges, smoke detectors, fill height detectors and in measuring ash content of coal.
Gd-148
Sr-90
Pm-147
F-18		Medical, aka FDG flourodeoxyglucose used in 90% of PET imaging
Ga-67		Medical
Re -186		Medical
I-123		Medical
Sm -153		Medical
Y-90		Medical
Er-169		Medical
Y-88
Sc-44
Ir-192		Fracking

Vendors

Perkinelmer

http://www.perkinelmer.com/Catalog/Category/ID/Radionuclides

Isoflex

http://www.isoflex.com/isotopes/ir192.html

@@ Line 281: / Line 281: @@
-Chromium 57:
-Used to label sand to study coastal erosion.
 Cobalt-60, Lanthanum-140, Scandium-46, Silver-110m, Gold-198:
 Used together in blast furnaces to determine resident times and to quantify yields to measure the furnace performance.
-Cobalt-60:
-Used for gamma sterilisation, industrial radiography, density and fill height switches.
-Gold-198 & Technetium-99m:
-Used to study sewage and liquid waste movements, as well as tracing factory waste causing ocean pollution, and to trace sand movement in river beds and ocean floors.
-Gold-198:
-Used to label sand to study coastal erosion.
-Hydrogen-3 (Tritiated Water): Used as a tracer to study sewage and liquid wastes
@@ Line 321: / Line 297: @@
 |Cesium-137|| ||Used for radiotracer technique for identification of sources of soil erosion and deposition, in density and fill height level switches.
 |-
-| Gd-148 ||  ||
+|Chromium 57|| ||Used to label sand to study coastal erosion.
+|-
+|Cobalt-60 || || Used for gamma sterilisation, industrial radiography, density and fill height switches.
+|-
+| Gadolinium-148 ||  ||
+|-
+|  Gold-198 ||  || Used to study sewage and liquid waste movements, as well as tracing factory waste causing ocean pollution, and to trace sand movement in river beds and ocean floors.
 |-
 | Iridium-192 ||<math>{193 \atop\; }Ir (\gamma,n){192 \atop \; }Ir</math> ||  Fracking ,Used in gamma radiography to locate flaws in metal components.
@@ Line 336: / Line 318: @@
 |-
 | Strontium-90 ||  ||Used for industrial gauging
+|-
+| Technetium-99m|| ||Used to study sewage and liquid waste movements, as well as tracing factory waste causing ocean pollution, and to trace sand movement in river beds and ocean floors.
 |-
 |Thallium-204|| ||Used for industrial gauging.

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