Difference between revisions of "NSF-MRI 2013"

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(Created page with "==Purpose== In June of 2012, the Idaho Accelerator Center received a grant from the state of Idaho as part of the Idaho Global Entrepreneurial Mission (IGEM) program. One of th…")
 
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==Purpose==
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\section{Introduction}
  
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In June of 2012, the Idaho Accelerator Center received a grant from the state of Idaho as part of the Idaho Global Entrepreneurial Mission (IGEM) program.  One of the proposed objectives was to research the use of an electron accelerator to the produce Copper isotopes to be used in medical diagnostic procedures.  Preliminary results of the work sponsored by this research have indicated that the production of Copper isotopes strongly depends on the alignment of incident radiation to the sample.  While a sample size of 2 cm may produce the highest number of isotopes per volume, a missalignment of more than a centimeter may reduce the amount of isotopes produced by a factor of at least two.  A strong need now exists for a system to monitor the spatial distribution of the photons used to irradiate the samples.  Based on these results, we propose the development of an irradiation instrument, that qualifies for the MRI category "Track 2", to be used for isotope production and PAA analysis.
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In June of 2012, the Idaho Accelerator Center received a grant from the state of Idaho as part of the Idaho Global Entrepreneurial Mission (IGEM) program.  One of the proposed objectives was to research the use of an electron accelerator to produce copper isotopes for use in medical diagnostic procedures.   
 +
Preliminary results of the work sponsored by this research have indicated that the production of copper isotopes strongly depends on the alignment of incident radiation to the sample.   
 +
While a sample size of 2 cm is predicted to produce the highest number of isotopes per volume, a misalignment of more than a centimeter may reduce the amount of isotopes produced by a factor of at least two.   
 +
A strong need now exists for a system to monitor the spatial distribution of the photons used to irradiate the samples.   
 +
There is also a need to transport samples into and out of the radiation area. 
 +
Based on these results, we propose to develop an instrument, that qualifies for the MRI category ``Track 2'', that will be used to produce isotopes and perform Photon Activation Analysis (PAA) services.
  
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The proposed instrument will be composed of a photon beam monitoring system and a sample conveyor.  Support from this MRI will be used to construct the photon monitoring system.  Matching support from the IGEM project will be used for the sample conveyor system.  The conveyor, commonly referred to as a rabbit, will transport samples into the irradiation region and then to a shielded container (lead pig) after irradiation.  The transportation system is a necessity due to the high activity isotopes that may be produced.  When used as an instrument for PAA, the transportation system will eliminate the step of shutting the accelerator off in order to change to the control sample thereby risking  a change in the experimental conditions whose uniformity is essential for meaningful measurements.  Once calibrated, the photon monitoring system would allow users to irradiate sample with a known amount of radiation.
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\section{Information about the Proposal (a)}
  
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The proposed instruments ability to enhance the production of copper isotopes for medical diagnostic tests is only one potential use.  Isotope production in the US is a $$$ busines..
 
  
 +
The proposed instrument will be composed of a photon beam monitoring system and a sample conveyor. 
 +
Support from this MRI will be used to purchase the components for a photon monitoring system. 
 +
Matching support from the IGEM project will be used to design and install a sample conveyor system while the MRI will purchase the system components. 
 +
The conveyor, commonly referred to as a rabbit, will transport samples into the irradiation region and then to a shielded container (lead pig) after irradiation. 
 +
The transportation system is a necessity due to the high activity isotopes that may be produced. 
 +
When used as an instrument for PAA, the transportation system will eliminate the step of shutting the accelerator off in order to change to the control sample thereby risking  a change in the experimental conditions whose uniformity is essential for meaningful measurements. 
 +
Once calibrated, the photon monitoring system would allow users to irradiate sample with a known amount of radiation.
 +
\\
  
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Paragraph of the instruments impact on the production of isotopes.
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Physical location: Idaho Accelerator Center, Pocatello, ID
  
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Using the instrument for PAA and the large potential user base.
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Instrument type: MRI-61
  
  
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The University of Missouri's Research Reactor is a current producer of medical isotopes with a total operating budget o
 
  
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==Talking points==
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\section{Research Activities to be Enabled (b)}
 +
The propose instrument will provide a means to more effectively produce isotopes and perform Photon Activation Analysis. 
 +
The Idaho Accelerator Center has a history of irradiating materials for outside users across disciplines from Biology to Archaeology.
 +
The production of isotopes, currently being pursued to provide medical sources, may also find consumers in industry.  PAA has been demonstrated as a useful tool in several IAC research projects already. 
 +
We believe a facility providing this service will find customers in fields ranging from Archaeology to mining and even coffee producers.
  
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1.) The accelerator "Jack" is an instrument for PAA and isotope production
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\section{Description of Research Instrumentation and Needs (c)}
  
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2.) Isotope production impact on other areas of research (medical, fracking, underground pipelines, spikants for homeland security)
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The proposed instrument will be composed of hardware used to position and monitor the incident radiation and a device to transport samples in and out of the radiation environment.
 +
Beam position monitors will be purchased to monitor the incident electron beam from the IAC accelerator on the radiator target.
 +
The position of the electrons on the radiator target effects the quality of the photons produced to irradiate samples. 
 +
A set of photon detectors (CVD diamond films) will be purchased and placed strategically around the beam line in order to tune the accelerator such that the photon flux is centered on the target.  A data acquisition system will be purchased to monitor this radiation flux.
 +
A conveyor system will be designed and installe to transport samples into and out of the radiation area.
  
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3.) Inter organizational use of PAA ( Geology, Archeology, certification for coffee origins....)
 
  
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4.) Impact of Photon Flux monitoring for PAA analysis
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\section{Impact on Research and Training Infrastructure (d)}
  
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5.) Device will train accelerator physicists, nuclear chemists, ...
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The proposed instrument will be a facility for performing isotope production research and training accelerator physicists.  
 +
The research on copper isotopes is well underway and quickly approaching a point where production for consumption is likely.
 +
The production of other isotopes for industry and research will also be under investigation using this device. The goal will be for the instrument to be self sustaining and a means of training students.
  
 +
The instrument will be an opportunity to train students in the operation of an electron accelerator as well as the techniques for isotope production and PAA.
 +
Graduate students, once trained, would operate the accelerator as a means of supporting their studies at ISU. 
  
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==Budget==
 
  
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Equipment list
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\section{Management Plan (e)}
  
 +
The IAC has a well established record of managing a facility that attracts researchers who purchase beam time.  This proposal seeks to expand the services that the IAC can provide.
 +
The components used to develop this instrument may be considered ``off the shelf''.  The accelerator expertise of the IAC and the detector development expertise of the PI will be relied upon to construct a working instrument. The track records of both entities are quite sound for this project. 
 +
The long term operations and maintenance plan will rely on the instruments ability to attract customers. 
 +
The growth of demand for medical isotopes and the continued warning of an isotop production crisis by the Department of Energy is a strong indication that the instrument will be in demand should its ability to produce isotopes become well established.
  
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two steps
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\section{Budget}
  
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1.) purchase 16, single crystal detectors from http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf.  These will serve as monitors distributed symmetrically around the beam line and used to steer the electron beam until equal photon rates are observed => centered photon beam.
 
  
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2.) A wire tungsten wire coated with diamond will sweep through the photon beam in the location of the target to measure the photon flux.
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\begin{table}[h]
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\begin{center}
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\begin{tabular}{ccc}
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\multicolumn{1}{c}{Cost} &
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\multicolumn{1}{c}{Match} &
 +
\multicolumn{1}{c}{Description} \\
 +
\hline\hline
  
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50,000 & N & 4 electron Beam Position Monitors\\
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get http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf to build a pixelated 3 x 3 cm detector with .5 x .5 cm size pixels (36 pixels)
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20,000 & N & CVD diamond detectors \\
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OR if the photon flux is too high construct a wire array.
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28,000 & N & Data Acquisition System \\
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50,000 & N & Conveyor system for isotope samples \\
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22,000 & Y & end station \\
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{| border="1"  |cellpadding="20" cellspacing="0
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50,000 & Y & Professional \& Technical Services \\
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|-
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\hline
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| Cost || Device || Purpose
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\end{tabular}
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|-
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\caption{Budget: Total expenses = \$220,000, Available Match \$72,000 (33 \%)}
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|  50,000 || BPMs || 4 electron beam position monitors
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\end{center}
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|-
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\label{table:Projects}
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| 20,000 ||16,  CVD Diamond detector || Off the shelf single crystal single pixel detector pg 49 in[ http://www.npl.co.uk/upload/pdf/091104_nuc_galbiati.pdf]
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\end{table}
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|-
 
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| 10,000 || 20 , 5 x 5 mm^2 CVD films || films for pixel detector array or wire (tungsten coated with diamond) scanner
 
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|-
 
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| 10,000 || Circuitry || PCB board, connectors, and single crystal mounting by external vendor
 
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|-
 
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| 30,000 || beam time || 3 weeks of beam time to test device and measure performance
 
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|-
 
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|$28,000 ||DAQ || VME based DAQ system with EPICs monitoring, 32 channel ADC ($6k), ROC($3k), MiniCrate($4k), Server ($2k), Tigger supervisor ($3k), NIM Discriminator /Trigger/ECL output module ($10k)
 
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|-
 
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| $10k Cost Share || Beam Line components || Steering coils ($1k), power supplies ($4k), and Beam line components($5k) to install BPMs
 
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|-
 
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| $160k Cost Share || Rabbit || sample conveyor system from IGEM grant
 
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|-
 
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|}
 
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;Proposed Budget:  $148k + $160k (Cost share) = $308k
 

Revision as of 00:10, 11 December 2012

\section{Introduction}

In June of 2012, the Idaho Accelerator Center received a grant from the state of Idaho as part of the Idaho Global Entrepreneurial Mission (IGEM) program. One of the proposed objectives was to research the use of an electron accelerator to produce copper isotopes for use in medical diagnostic procedures. Preliminary results of the work sponsored by this research have indicated that the production of copper isotopes strongly depends on the alignment of incident radiation to the sample. While a sample size of 2 cm is predicted to produce the highest number of isotopes per volume, a misalignment of more than a centimeter may reduce the amount of isotopes produced by a factor of at least two. A strong need now exists for a system to monitor the spatial distribution of the photons used to irradiate the samples. There is also a need to transport samples into and out of the radiation area. Based on these results, we propose to develop an instrument, that qualifies for the MRI category ``Track 2, that will be used to produce isotopes and perform Photon Activation Analysis (PAA) services.

\section{Information about the Proposal (a)}


The proposed instrument will be composed of a photon beam monitoring system and a sample conveyor. Support from this MRI will be used to purchase the components for a photon monitoring system. Matching support from the IGEM project will be used to design and install a sample conveyor system while the MRI will purchase the system components. The conveyor, commonly referred to as a rabbit, will transport samples into the irradiation region and then to a shielded container (lead pig) after irradiation. The transportation system is a necessity due to the high activity isotopes that may be produced. When used as an instrument for PAA, the transportation system will eliminate the step of shutting the accelerator off in order to change to the control sample thereby risking a change in the experimental conditions whose uniformity is essential for meaningful measurements. Once calibrated, the photon monitoring system would allow users to irradiate sample with a known amount of radiation. \\

Physical location: Idaho Accelerator Center, Pocatello, ID

Instrument type: MRI-61


\section{Research Activities to be Enabled (b)} The propose instrument will provide a means to more effectively produce isotopes and perform Photon Activation Analysis. The Idaho Accelerator Center has a history of irradiating materials for outside users across disciplines from Biology to Archaeology. The production of isotopes, currently being pursued to provide medical sources, may also find consumers in industry. PAA has been demonstrated as a useful tool in several IAC research projects already. We believe a facility providing this service will find customers in fields ranging from Archaeology to mining and even coffee producers.

\section{Description of Research Instrumentation and Needs (c)}

The proposed instrument will be composed of hardware used to position and monitor the incident radiation and a device to transport samples in and out of the radiation environment. Beam position monitors will be purchased to monitor the incident electron beam from the IAC accelerator on the radiator target. The position of the electrons on the radiator target effects the quality of the photons produced to irradiate samples. A set of photon detectors (CVD diamond films) will be purchased and placed strategically around the beam line in order to tune the accelerator such that the photon flux is centered on the target. A data acquisition system will be purchased to monitor this radiation flux. A conveyor system will be designed and installe to transport samples into and out of the radiation area.


\section{Impact on Research and Training Infrastructure (d)}

The proposed instrument will be a facility for performing isotope production research and training accelerator physicists. The research on copper isotopes is well underway and quickly approaching a point where production for consumption is likely. The production of other isotopes for industry and research will also be under investigation using this device. The goal will be for the instrument to be self sustaining and a means of training students.

The instrument will be an opportunity to train students in the operation of an electron accelerator as well as the techniques for isotope production and PAA. Graduate students, once trained, would operate the accelerator as a means of supporting their studies at ISU.


\section{Management Plan (e)}

The IAC has a well established record of managing a facility that attracts researchers who purchase beam time. This proposal seeks to expand the services that the IAC can provide. The components used to develop this instrument may be considered ``off the shelf. The accelerator expertise of the IAC and the detector development expertise of the PI will be relied upon to construct a working instrument. The track records of both entities are quite sound for this project. The long term operations and maintenance plan will rely on the instruments ability to attract customers. The growth of demand for medical isotopes and the continued warning of an isotop production crisis by the Department of Energy is a strong indication that the instrument will be in demand should its ability to produce isotopes become well established.

\section{Budget}


\begin{table}[h] \begin{center} \begin{tabular}{ccc} \multicolumn{1}{c}{Cost} & \multicolumn{1}{c}{Match} & \multicolumn{1}{c}{Description} \\ \hline\hline

50,000 & N & 4 electron Beam Position Monitors\\ 20,000 & N & CVD diamond detectors \\ 28,000 & N & Data Acquisition System \\ 50,000 & N & Conveyor system for isotope samples \\ 22,000 & Y & end station \\ 50,000 & Y & Professional \& Technical Services \\ \hline \end{tabular} \caption{Budget: Total expenses = \$220,000, Available Match \$72,000 (33 \%)} \end{center} \label{table:Projects} \end{table}

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