Difference between revisions of "TF Antimony"
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=Tellurium(Te) to Antimony(Sb)= | =Tellurium(Te) to Antimony(Sb)= | ||
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| + | A pure Tellurium foils is immersed in a bremstraahlung beam to eject a proton from Te-120 leaving the Antimony isotope Se-119. | ||
\gamma + Te-120 -> Sb-119 + p | \gamma + Te-120 -> Sb-119 + p | ||
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Sb-117 is a PET analog => in 2 hrs Sb-117 decays emitting a positron that will annihilate and produce two 511 keV photons for a PET imager to detect. | Sb-117 is a PET analog => in 2 hrs Sb-117 decays emitting a positron that will annihilate and produce two 511 keV photons for a PET imager to detect. | ||
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| + | Theranostic is an therapy with companion atoms. One atom serves as the radiological therapy and the other atom emits radiation that is detectable to a diagnostic device. For example Sb-119 emits low energy auger electrons to kill cancer cells while Sb-117 beta decays emitting a positron that annihilates and emits two 511 photons that are detectable by a PET scanner. The half life of Sb-117 is less than 3 hours and the half life of Sb-119 is 38 hours. | ||
=References= | =References= | ||
Revision as of 18:11, 31 July 2020
Antiomony(Sb)
Tellurium(Te) to Antimony(Sb)
A pure Tellurium foils is immersed in a bremstraahlung beam to eject a proton from Te-120 leaving the Antimony isotope Se-119.
\gamma + Te-120 -> Sb-119 + p
Sb-119 is an Auger electron emitter
Sb-117 is a PET analog => in 2 hrs Sb-117 decays emitting a positron that will annihilate and produce two 511 keV photons for a PET imager to detect.
Theranostic is an therapy with companion atoms. One atom serves as the radiological therapy and the other atom emits radiation that is detectable to a diagnostic device. For example Sb-119 emits low energy auger electrons to kill cancer cells while Sb-117 beta decays emitting a positron that annihilates and emits two 511 photons that are detectable by a PET scanner. The half life of Sb-117 is less than 3 hours and the half life of Sb-119 is 38 hours.
References
Accelerator based Production of Auger-Electron-emitting Isotopes for Radionuclide Therapy Helge ThisgaardR, PhD-theis, pg 22; Thesis may have led to this publication Thisgaard H.; Jensen M. Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron. Appl. Radiat. Isot. 2009, 67, 34–38.
The Paradox of Using Radionuclides To Treat Disease, Thomas E. Albrecht-Schmitt, ACS Cent Sci. 2019 Mar 27; 5(3): 383–385